When the Truth Is Shown to Be Lies
Frank Cocozzelli printable version print page     Bookmark and Share
Sun Mar 07, 2010 at 06:30:50 PM EST
It's been a year since President Obama lifted the Bush administration's restrictions on the federal funding of embryonic stem cell research.  Nevertheless, religious opponents of the research still claim that embryonic stem cells have yet to yield any treatments. They insist that adult stem cell research will render embryonic stem cell research unnecessary.

Well, guess what?

The Religious Right's position on this recently took a big hit with this news:

Massachusetts based biotech company Advanced Cell Technology recently announced that the FDA has granted orphan drug status to MA09-hRPE - an embryonic stem cell derived treatment for a specific form of blindness (Stargardt's Macular Dystrophy). Orphan drug status is targeted to those therapies which are designed to treat fewer than 200,000 Americans and gives ACT access to tax credits, grants for clinical trials, and a seven year exclusivity to market MA09-hRPE. This is the first such FDA approval for an embryonic stem cell derived therapy and ACT plans on using the orphan drug status to accelerate clinical testing. While Advanced Cell Technology has something of a checkered past, this recent FDA status could signal not only an approaching success for the MA09-hRPE treatment, but also a promising advancement in the company's goal to pioneer new forms of regenerative medicine.

But even as this good news demolishes the Religious Right's argument, it is not the first research to lead to potential treatments.  Early last year it was reported that "The U.S. Food and Drug Administration (FDA) gave the go-ahead for Geron Corporation to start a phase I safety trial of its therapy GRNOPC1 for spinal cord injuries." And prior to that, in 2008 Dr. Robert Lanza was able to create human blood from embryonic stem cells.

The Religious Right's claims that "adult stem cell research making embryonic stem cell research unnecessary" is both politically disingenuous and scientifically counter productive in so far as it has discouraged the search for treatments for disease and disability.

I've personally spoken with adult stem cell researchers who also firmly support embryonic stem cell research.  They have pointed out to me that both avenues must be pursued.

In 2006 I wrote about a seminar hosted by the Catholic Diocese of Brooklyn which promoted the Church's official position on stem cell research. I was there. Several of my co-religionists who oppose embryonic stem cell research repeatedly spoke about how embryonic stem cell will not yield cures, again singing the old refrain that there has yet to be a single cure from them. They also conveniently omitted how adult stem cell research has been going on since the 1930s -bone marrow transplanting is one form - while human embryonic stem cell research only began truly taking off in late 1998. Apparently this mendacity was even a bit much for guest speaker, neocon Eric Cohen. To his credit, Cohen chided his hosts that indeed the research will most likely result in treatments and perhaps cures. He pleaded with his fellow embryonic stem cell research opponents to voice their opposition on purely moral grounds.

And therein lies the rub. It is odd that religious opponents of embryonic stem cell research dissemble the facts on this important issue. Is it because they believe that their moral view on the subject is too weak or do they feel entitled to tell noble lies simply because, in their view, the ends justify the means.

I don't know the answer to that question. But I do know that any further use of this cherished argument may now be fairly described as an outright lie.




Display:
On the day this FDA has granted orphan drug status to MA09-hRPE - an embryonic stem cell derived treatment for a specific form of blindness (Stargardt's Macular Dystrophy) occurred my  Aunt Midge was buried.
She died from lung cancer but had this form of macular dystrophy.

She had lived long enough to have her great grandchild christened after her, but was never able to see this child.

I hope their is a cure for this and other afflictions.
the right wingers will only find other things or people to condemn. Their ability to hate is unlimited.

by mgardener on Wed Mar 10, 2010 at 01:50:05 PM EST


What will the Religious Right opponents of the research say if these treatments start becoming standard treatments? It may well be the ultimate in chutzpah.

by Frank Cocozzelli on Sun Mar 07, 2010 at 06:40:48 PM EST
How much do you want to bet they will take advantage of it?

by khughes1963 on Sun Mar 07, 2010 at 08:04:45 PM EST
Parent
I think there is a chance they may find a martyr, and (at least in the case of Catholics, an eventual candidate for sainthood).  See my comment below.

by tacitus on Mon Mar 08, 2010 at 01:25:15 AM EST
Parent
I just can't picture anyone, especially parents of a child afflicted with blindness, who would parade around the fact that they would deny their child the gift of sight just to win points in this debate.

And, even if they did find people so callous as to do this to someone they claim to love, maybe a fellow sibling or elderly friend who agreed to continue being blind, the backlash would be momentous, I'm sure.

Having opined thus, I do have to admit that the general American public has astounded me too many times in it's ability to close it's eyes to blatant unfairness, to actually put money on my assertion. It's imperative that the real science behind the stem-cell debate be disseminated more broadly, so that those who are not ideologues can better understand why this procedure is not murder or abortion.

by trog69 on Wed Mar 10, 2010 at 03:11:48 AM EST
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Dominionists- who in many cases are so brainwashed that they THINK they're helping people by harming them!!!


by ArchaeoBob on Wed Mar 10, 2010 at 09:09:17 AM EST
Parent





I think we need to be a little cautious here.  Neither treatment mentioned in the article has been proven to be effective yet, and having at one time followed the news on a number of drug trials for that horror of a disease, ALS, I know how hard it can be to turn a promising lab experiment into an effective treatment.

No doubt ACT sought orphan drug status as soon as it could to reduce the risk of their investment, and even though the early results are promising, it's definitely too early to be celebrating.

If it is successful (and I really hope it is) then it could present a couple of very interest scenarios within the ESCR debate.  SMD not a life threatening disease, so I suspect there is a reasonable chance that the anti-ESCR forces might find a martyr to their cause amongst those who are afflicted with ACT -- i.e. someone who prefers to go or stay blind rather than take advantage on an embryo-derived therapy.

Even more interesting (and a little worrying) is that SMD can start developing in children as young as six though it's not clear from the link at what age most people are diagnosed with the disease, since it starts slowly -- it is hereditary, so I guess they will be on the look out for it, however.

Now imagine if that kid is the child of conservative Catholic, or Protestant parents.  If it's a therapy that can save their child from a life of blindness but they refuse him or her treatment, then we could be looking at a legal case similar to those involving Christian Scientists or Jehovah's Witnesses.

So, I'm not entirely sure that either the ACT or the GRNOPC1 trials, if successful, are the Holy Grail of ESCR.  In the minds of those who are not fundamentally against ESCR I am sure they will be welcome news, but I suspect that until there is a treatment that actually saves lives as opposed to making someone's life better (a whole lot better, obviously) the battle will rage on.

I hope not, but I think all it will take is one poor deluded soul to refuse treatment (in either case) for the controversy to kick into an even higher gear.  We shall see.

by tacitus on Mon Mar 08, 2010 at 01:23:54 AM EST



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